Synthesis and NMR Characterization of Metal Complexes of Butanedione-Monoxime Thiosemicarbazones

Abstract

Thiosemicarbazones are versatile organic compounds that have biological and medicinal properties; additionally, they act as multi-dentate ligands for metal complexes. Our lab has successfully synthesized a series of new monoxime-thiosemicarbazones ligands. Specifically, butanedione monoxime ethyl (BDMO-ETSC) and tertbutyl-thiosemicarbazone (BDMO-tBTSC) have been reacted with Copper(II), Nickel (II), and Palladium(II) salts to give a series of monomeric and dimeric complex structures. These structures were analyzed using NMR spectroscopy in order to characterize the monomeric and dimeric stages. The differences are discussed in our findings.